Article
Restriction fragment length polymorphism (RFLP) heterogeneity of HLA-DQ beta genes associated with DNA fragment identical to the DR1-beta DNA structure.
Disease markers - 1 Jan 2000
Redford A, Magalong D, Onohara-Toyoda M, Tyan D, Riley W J, Maclaren N K, Rotter J I, Toyoda H
Abstract excerpt
Restriction fragment length polymorphism (RFLP) analyses of DR1 positive peripheral blood leukocytes DNA was carried out. The Taq I digested DNA was hybridized with cDNA probes for HLA-DR and -DQ beta genes. The DR probe detected fragments commonly observed in the DR1 specificity, whereas a new D...
Topics
- Alleles
- DNA
- DNA Probes
- Female
- Genes, MHC Class II
- HLA-DQ Antigens
- HLA-DQ beta-Chains
- HLA-DR Antigens
- HLA-DRB1 Chains
- Histocompatibility Antigens Class II
- Humans
- Male
- Polymorphism, Restriction Fragment Length