Isolation of the human LIM/homeodomain gene islet-1 and identification of a simple sequence repeat polymorphism [corrected].

doi:10.2337/diab.43.7.935

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Article

Isolation of the human LIM/homeodomain gene islet-1 and identification of a simple sequence repeat polymorphism [corrected].

Diabetes - 1 Jul 1994

Tanizawa Y, Riggs A C, Dagogo-Jack S, Vaxillaire M, Froguel P, Liu L, Donis-Keller H, Permutt M A

Abstract excerpt

The islet-1 (Isl-1) gene encodes a protein that binds to the enhancer region of the insulin gene. Isl-1 is a member of the LIM/homeodomain family of transcription factors. Because insulin deficiency, either relative or absolute, is a cardinal feature of non-insulin-dependent diabetes mellitus (NI...

Topics

Alleles
Asian People
Base Sequence
Black People
Chromosome Mapping
Chromosomes, Human, Pair 5
Consensus Sequence
DNA
DNA Primers
DNA-Binding Proteins
Diabetes Mellitus, Type 2
Enhancer Elements, Genetic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Gene Frequency

Genes, Homeobox

Genetic Linkage

Genetic Markers

Glucokinase

Homeodomain Proteins

Source

Open in PubMed

Identifiers

PMID: 7912209
DOI: 10.2337/diab.43.7.935

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7912209-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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Isolation of the human LIM/homeodomain gene islet-1 and identification of a simple sequence repeat polymorphism [corrected].PMID 7912209Read ↗

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