Article
Regulation by Rab3A of an endogenous modulator of neurotransmitter release at mouse motor nerve endings.
The Journal of physiology - 1 Dec 2002
Hirsh Jody K, Searl Timothy J, Silinsky Eugene M
Abstract excerpt
Rab3A, a small GTP-binding protein attached to synaptic vesicles, has been implicated in several stages in the process of neurosecretion, including a late stage occurring just prior to the actual release of neurotransmitter. The inhibitory neuromodulator adenosine also targets a late step in the neurosecretory pathway. We thus compared neuromuscular junctions from adult Rab3A(-/-) mutant mice with those from...
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