Article
Gene inactivation in Drosophila mediated by the Polycomb gene product or by position-effect variegation does not involve major changes in the accessibility of the chromatin fibre.
Molecular & general genetics : MGG - 25 May 1994
Schlossherr J, Eggert H, Paro R, Cremer S, Jack R S
Abstract excerpt
In Drosophila position effect variegation and Polycomb-dependent regulation of homeotic gene expression are phenomena in which genes are inactivated in a clonally inherited manner. In both processes inactivation involves proteins that interact with the chromosome at or close to the position of in...
Topics
- Animals
- Base Sequence
- Cell Nucleus
- Chromatin
- Chromosomal Proteins, Non-Histone
- Chromosomes
- DNA-Binding Proteins
- Drosophila Proteins
- Drosophila melanogaster
- Enhancer Elements, Genetic
- Eye Color
- Female
- Gene Expression Regulation
- Genes, Homeobox