Article
Production of bioactive rabbit antibodies against the mutated receptor peptide TSH-R-HIS17 and detection of hypertriiodothyroninemia in the rabbit.
Biochemistry and molecular biology international - 1 Mar 1993
Hirooka Y, Mitsuma T, Nogimori T, Ishizuki Y, Sakai J, Naruse M, Fukayama M
Abstract excerpt
We produced rabbit antibodies against mutated thyrotropin (TSH) receptor peptide TSH-R-HIS17 in comparison with non-mutated TSH receptor peptide TSH-R-ASP17. All the antibodies raised against TSH-R-HIS17 showed thyroid stimulating antibody (TSAb), thyroid stimulation blocking antibody (TSBAb) and...
Topics
- Amino Acid Sequence
- Animals
- Aspartic Acid
- Autoantibodies
- Histidine
- Immunoglobulins, Thyroid-Stimulating
- Molecular Sequence Data
- Mutation
- Peptide Fragments
- Rabbits
- Receptors, Thyrotropin
- Triiodothyronine