Article
Dominant expression of multidrug resistance in intraspecific murine lymphoma hybrid cells.
Cancer chemotherapy and pharmacology - 1 Jan 1994
Pályi I, Turi G, Hullán L, Szikla K, Bak M
Abstract excerpt
Cultured P388/VCR mouse lymphoma cells resistant to vincristine (VCR) and to 5-bromodeoxyuridine (BUdR) and deficient in thymidine kinase (TK-) were fused with P388/DAG cells resistant to 1.2:5,6-dianhydrogalactitol (DAG), an anticancer alkylating agent, and to 6-thioguanine (6-TG) and deficient...
Topics
- ATP Binding Cassette Transporter, Subfamily B, Member 1
- Animals
- Antineoplastic Agents
- Bromodeoxyuridine
- Carrier Proteins
- Cell Fusion
- Cell Survival
- Dactinomycin
- Dianhydrogalactitol
- Dose-Response Relationship, Drug
- Doxorubicin
- Drug Resistance
- Gene Expression
- Hybrid Cells
- Hypoxanthine Phosphoribosyltransferase
- Immunoenzyme Techniques
- Karyotyping
- Lymphoma