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Article

The relationship of TAP1 and TAP2 dimorphisms to multiple sclerosis susceptibility.

Journal of neuroimmunology - 1 Jun 1995

Bell R B, Ramachandran S

Abstract excerpt

Transporters associated with antigen processing and presentation (TAP1 and TAP2) have been considered candidate genes in MS susceptibility based on evidence from experimental animal models confirming antigenic peptide selection by transporter polymorphisms and by the proximity of these transporter genes to the DR- and DQ-associated alleles known to confer disease risk in man. We report here an association study...

Topics

ATP Binding Cassette Transporter, Subfamily B, Member 2
ATP Binding Cassette Transporter, Subfamily B, Member 3
ATP-Binding Cassette Transporters
Alleles
Disease Susceptibility
HLA-DQ Antigens
HLA-DR Antigens
Humans
Multiple Sclerosis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 7797617
DOI: 10.1016/0165-5728(95)00046-5

Genes

TAP1
TAP2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7797617-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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The relationship of TAP1 and TAP2 dimorphisms to multiple sclerosis susceptibility.PMID 7797617Read ↗

TAP 1 and TAP 2 transporter gene polymorphisms in multiple sclerosis: no evidence for disease association with TAP.Semantic proximity Read ↗

MHC-encoded TAP1 and TAP2 dimorphisms in multiple sclerosis.Semantic proximity Read ↗

TAP2 gene polymorphism contributes to genetic susceptibility to multiple sclerosis.Semantic proximity Read ↗

No association of multiple sclerosis to alleles at the TAP2 locus.Semantic proximity Read ↗

TAP2 polymorphisms in Australian multiple sclerosis patients.Semantic proximity Read ↗

Analysis of the MHC-encoded transporters TAP1 and TAP2 in rheumatoid arthritis: linkage with DR4 accounts for the association with a minor TAP2 allele.Semantic proximity Read ↗

TAP1 and TAP2 polymorphism in coeliac disease.Semantic proximity Read ↗

Tap gene associations in UK caucasoids.Semantic proximity Read ↗

Polymorphism of human major histocompatibility complex-encoded transporter associated with antigen processing (TAP) genes and susceptibility to juvenile rheumatoid arthritis.Semantic proximity Read ↗

TAP2D is associated with HLA-B44 and DR4 and may contribute to rheumatoid arthritis and Felty's syndrome susceptibility.Semantic proximity Read ↗

TAP1 and TAP2 polymorphism in HLA-B27-positive subpopulations: no allelic differences in ankylosing spondylitis and reactive arthritis.Semantic proximity Read ↗

TAP2 association with insulin-dependent diabetes mellitus is secondary to HLA-DQB1.Semantic proximity Read ↗

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