Article
Insertion/deletion polymorphism in the angiotensin-I-converting enzyme gene is associated with coronary heart disease in IDDM patients with diabetic nephropathy.
Diabetologia - 1 Jul 1995
Tarnow L, Cambien F, Rossing P, Nielsen F S, Hansen B V, Lecerf L, Poirier O, Danilov S, Boelskifte S, Borch-Johnsen K
Abstract excerpt
Insulin-dependent diabetic (IDDM) patients with diabetic nephropathy have a highly increased morbidity and mortality from coronary heart disease. An insertion (I) /deletion (D) polymorphism in the angiotensin-I-converting enzyme (ACE) gene has been shown to be associated with coronary heart disea...
Topics
- Adult
- Aged
- Albuminuria
- Analysis of Variance
- Blood Pressure
- Coronary Disease
- Creatinine
- Cross-Sectional Studies
- DNA Transposable Elements
- Diabetes Mellitus, Type 1
- Diabetic Angiopathies
- Diabetic Nephropathies
- Female
- Genotype
- Humans