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Article

Insertion/deletion polymorphism in the angiotensin-I-converting enzyme gene is associated with coronary heart disease in IDDM patients with diabetic nephropathy.

Diabetologia - 1 Jul 1995

Tarnow L, Cambien F, Rossing P, Nielsen F S, Hansen B V, Lecerf L, Poirier O, Danilov S, Boelskifte S, Borch-Johnsen K

Abstract excerpt

Insulin-dependent diabetic (IDDM) patients with diabetic nephropathy have a highly increased morbidity and mortality from coronary heart disease. An insertion (I) /deletion (D) polymorphism in the angiotensin-I-converting enzyme (ACE) gene has been shown to be associated with coronary heart disease. Therefore, we have investigated the role of this ACE/ID polymorphism in 198 IDDM patients with diabetic nephropathy...

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Source

Identifiers

PMID: 7556981
DOI: 10.1007/s001250050355

Genes

ACE

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Insertion/deletion polymorphism in the angiotensin-I-converting enzyme gene is associated with coronary heart disease in IDDM patients with diabetic nephropathy.PMID 7556981Read ↗

Evaluation of risk factors for the development of nephropathy in patients with IDDM: insertion/deletion angiotensin converting enzyme gene polymorphism, hypertension and metabolic control.Semantic proximity Read ↗

The deletion/insertion polymorphism of the angiotensin converting enzyme gene and cardiovascular-renal risk.Semantic proximity Read ↗

Lack of association between the insertion/deletion polymorphism of the angiotensin-converting-enzyme gene and diabetic nephropathy in IDDM patients.Semantic proximity Read ↗

Angiotensin-converting enzyme gene and diabetes mellitus.Semantic proximity Read ↗

ACE insertion/deletion polymorphism and diabetic nephropathy: clinical implications of genetic information.Semantic proximity Read ↗

The DD genotype of the ACE gene polymorphism is associated with diabetic nephropathy in the type-1 diabetics.Semantic proximity Read ↗

Deletion polymorphism in the gene for angiotensin-converting enzyme is a potent risk factor for myocardial infarction.Semantic proximity Read ↗

Angiotensin converting enzyme gene I/D polymorphism in essential hypertension and nephroangiosclerosis.Semantic proximity Read ↗

Angiotensin-converting enzyme polymorphism and development of diabetic nephropathy in non-insulin-dependent diabetes mellitus.Semantic proximity Read ↗

Angiotensin I-converting enzyme insertion/deletion polymorphism: clinical implications.Semantic proximity Read ↗

Antiproteinuric effect of losartan in non-diabetic renal disease is not dependent on ACE insertion/deletion polymorphism.Semantic proximity Read ↗

Insertion/deletion polymorphism of the angiotensin-converting enzyme gene is strongly associated with coronary heart disease in non-insulin-dependent diabetes mellitus.Semantic proximity Read ↗

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