Article
Association between the angiotensin-converting enzyme-insertion/deletion polymorphism and diabetic nephropathy: a methodologic appraisal and systematic review.
Journal of the American Society of Nephrology : JASN - 1 Sept 1998
Kunz R, Bork J P, Fritsche L, Ringel J, Sharma A M
Abstract excerpt
Recent studies have implicated a variant of the angiotensin-converting enzyme gene (ACE), associated with increased activity of this enzyme, in the development and progression of diabetic nephropathy. This study provides a systematic review of all cross-sectional, case-control, and cohort studies...
Topics
- Adult
- Aged
- Female
- Humans
- Male
- Middle Aged
- Age Distribution
- Asian People
- Case-Control Studies
- Cohort Studies
- Confidence Intervals
- Confounding Factors, Epidemiologic
- Cross-Sectional Studies
- Diabetes Mellitus, Type 1
- Diabetes Mellitus, Type 2
- Diabetic Nephropathies
- Gene Expression
- Genotype