Article
MTHFR C677T, A1298C and ACE I/D polymorphisms as risk factors for diabetic nephropathy among type 2 diabetic patients.
Journal of the renin-angiotensin-aldosterone system : JRAAS - 1 Dec 2012
El-Baz Rizk, Settin Ahmad, Ismaeel Azza, Khaleel Abd Allah, Abbas Tarek, Tolba Wafaa, Abd Allah Wafaa, Sobh Mohammed Abd El-Kader
Abstract excerpt
BACKGROUND: Genetic variations have been proposed to play a role in the susceptibility to diabetic nephropathy. OBJECTIVES: To check for the association of genetic polymorphisms of methylenetetrahydrofolate reductase (MTHFR) and angiotensin converting enzyme (ACE) genes with the development of diabetic nephropathy among type 2 diabetic patients. METHODS: Participants comprised 202 patients with type 2 diabetes,...
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