[URE3] as an altered URE2 protein: evidence for a prion analog in Saccharomyces cerevisiae.

doi:10.1126/science.7909170

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Article

[URE3] as an altered URE2 protein: evidence for a prion analog in Saccharomyces cerevisiae.

Science (New York, N.Y.) - 22 Apr 1994

Wickner R B

Abstract excerpt

A cytoplasmically inherited element, [URE3], allows yeast to use ureidosuccinate in the presence of ammonium ion. Chromosomal mutations in the URE2 gene produce the same phenotype. [URE3] depends for its propagation on the URE2 product (Ure2p), a negative regulator of enzymes of nitrogen metaboli...

Topics

Aspartic Acid
Base Sequence
Crosses, Genetic
Fungal Proteins
Genes, Dominant
Genes, Fungal
Genes, Recessive
Glutathione Peroxidase
Guanidine
Guanidines
Molecular Sequence Data
Mutation
Phenotype
Plasmids
PrPSc Proteins
Prions
Saccharomyces cerevisiae
Saccharomyces cerevisiae Proteins

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