Article
Tyrosine hydroxylase regulation in neurotransmission and neuroplasticity.
Journal of physiology, Paris - 1 Jan 1993
Icard-Liepkalns C, Berrard S, Faucon Biguet N, Lebourdelles B, Ravassard P, Robert J J, Mallet J
Abstract excerpt
The modulation of neurotransmitter synthesis is a fundamental mechanism influencing neurotransmission and neuronal plasticity during development. The regulation of the tyrosine hydroxylase (TH) has been used to elucidate specific adaptative responses in neurons. Trans-synaptic impulse activity elicits sort- and long-term changes in the activity of TH. Acute regulation involves the activation of preexisting TH...
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