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Article

Salt loading as a promising approach to study the dopaminergic phenotype of neurons of the supraoptic nucleus in mice.

PloS one - 1 Jan 2026

Bannikova Alyona E, Pronina Tatiana S, Troshev Dmitry V, Bogdanov Vsevolod V, Kolacheva Anna A, Pavlova Ekaterina N, Blokhin Victor E, Kalashnikova Varvara I, Ugrumov Michael V

Abstract excerpt

Until the beginning of this century, neurons of the supraoptic nucleus (SON) were repeatedly shown to express tyrosine hydroxylase (TH) in salt loaded rats. However, its role remains unsolved due to methodological problems. Given that these issues can now be solved using transgenic mice and more advanced methods, the aim of this study was to reproduce the salt loading models used in rats, in C57BL/6 mice and...

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Identifiers

PMID: 41650117
DOI: 10.1371/journal.pone.0340281
PMCID: PMC12880680

Genes

TH
SON

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