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Article

Calcium spike underlying rhythmic firing in dopaminergic neurons of the rat substantia nigra.

Neuroscience research - 1 Dec 1993

Kang Y, Kitai S T

Abstract excerpt

In order to study a possible mechanism for rhythmic firing of dopaminergic (DA) neurons, intracellular recordings were obtained from 56 rhythmically firing DA neurons in the rat substantia nigra compacta (SNc), using in vitro slice preparations. In the presence of TTX, spontaneous oscillation of the membrane potential was induced in SNc DA neurons when the membrane potential was depolarized more positive from -60...

Topics

Action Potentials
Animals
Calcium
Dopamine
Electrophysiology
Immunohistochemistry
Male
Membrane Potentials
Neurons
Phenotype
Rats
Rats, Sprague-Dawley

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Substantia Nigra

Tetrodotoxin

Tyrosine 3-Monooxygenase

Source

Identifiers

PMID: 7907413
DOI: 10.1016/0168-0102(93)90055-u

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7907413-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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