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Article

Activity-dependent regulation of the dopamine phenotype in substantia nigra neurons.

Journal of neurochemistry - 1 May 2012

Aumann Tim, Horne Mal

Abstract excerpt

Degeneration of dopamine (DA) neurons in the substantia nigra pars compacta (SNc) causes the motor symptoms of Parkinson's disease. The development of cell-replacement therapies for Parkinson's disease motor symptoms is hampered by poor acquisition and retention of the DA phenotype by endogenous and transplanted neurons. Factors which regulate the DA phenotype in the adult SNc are, therefore, keenly sought....

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Identifiers

PMID: 22356203
DOI: 10.1111/j.1471-4159.2012.07703.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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