Ionic factors governing rebound burst phenotype in rat deep cerebellar neurons.

doi:10.1152/jn.90427.2008

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Article

Ionic factors governing rebound burst phenotype in rat deep cerebellar neurons.

Journal of neurophysiology - 1 Nov 2008

Molineux Michael L, Mehaffey W Hamish, Tadayonnejad Reza, Anderson Dustin, Tennent Adrien F, Turner Ray W

Abstract excerpt

Large diameter cells in rat deep cerebellar nuclei (DCN) can be distinguished according to the generation of a transient or weak rebound burst and the expression of T-type Ca(2+) channel isoforms. We studied the ionic basis for the distinction in burst phenotypes in rat DCN cells in vitro. Following a hyperpolarization, transient burst cells generated a high-frequency spike burst of < or = 450 Hz, whereas weak...

Topics

Action Potentials
Animals
Animals, Newborn
Cadmium
Calcium
Calcium Channels
Cerebellum
Electric Stimulation
In Vitro Techniques
Ion Channel Gating
Microtubule-Associated Proteins
Neurons
Nickel
Patch-Clamp Techniques
Phenotype
Potassium Channel Blockers
Potassium Channels
Rats

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Open in PubMed

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PMID: 18768644
DOI: 10.1152/jn.90427.2008

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