Article
Anti-beta-receptor antibodies in familial cardiomyopathy: correlation with HLA-DR and HLA-DQ gene polymorphisms.
American heart journal - 1 Feb 1994
Limas C, Limas C J, Boudoulas H, Bair R, Graber H, Sparks L, Wooley C F
Abstract excerpt
The presence of beta-receptor autoantibodies and their relationship to restriction fragment length polymorphisms of the human leukocyte antigen (HLA) class II genes were studied in 42 affected and unaffected members of a family with a heritable disorder of the conduction system and cardiac muscle...
Topics
- Arrhythmias, Cardiac
- Autoantibodies
- Biomarkers
- Cardiomegaly
- Cardiomyopathy, Dilated
- Disease Susceptibility
- Female
- Genes, MHC Class II
- Genetic Predisposition to Disease
- HLA-DQ Antigens
- HLA-DR Antigens
- HLA-DR4 Antigen
- Heart Block
- Heart Failure
- Humans
- Male
- Phenotype
- Polymorphism, Genetic