A meta-analysis of HLA-DR polymorphism and genetic susceptibility to idiopathic dilated cardiomyopathy.

doi:10.1007/s11033-011-0729-y

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Article

A meta-analysis of HLA-DR polymorphism and genetic susceptibility to idiopathic dilated cardiomyopathy.

Molecular biology reports - 1 Jan 2012

Jin Bo, Luo Xin-Ping, Ni Huan-Chun, Shen Wei, Shi Hai-Ming, Li Yong

Abstract excerpt

Idiopathic dilated cardiomyopathy (IDC) has been hypothesized as a multifactorial disorder initiated by an environment trigger in individuals with predisposing human leukocyte antigen (HLA) alleles. Published data on the association between HLA-DR polymorphism and IDC risk are inconclusive. To derive a more precise estimation of the relationship, a meta-analysis was performed. A total of 19 case-control studies...

Topics

Cardiomyopathy, Dilated
Case-Control Studies
Genetic Association Studies
Genetic Predisposition to Disease
HLA-DR Antigens
Humans
Polymorphism, Genetic
Sensitivity and Specificity

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Open in PubMed

Identifiers

PMID: 21556773
DOI: 10.1007/s11033-011-0729-y

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