Article
Dominant unc-37 mutations suppress the movement defect of a homeodomain mutation in unc-4, a neural specificity gene in Caenorhabditis elegans.
Genetics - 1 Nov 1993
Miller D M, Niemeyer C J, Chitkara P
Abstract excerpt
The unc-4 gene of Caenorhabditis elegans encodes a homeodomain protein that defines synaptic input to ventral cord motor neurons. unc-4 mutants are unable to crawl backward because VA motor neurons are miswired with synaptic connections normally reserved for their sister cells, the VB motor neuro...
Topics
- Alleles
- Amino Acid Sequence
- Animals
- Caenorhabditis elegans
- Female
- Genes, Dominant
- Genes, Helminth
- Genes, Homeobox
- Genes, Suppressor
- Genetic Linkage
- Helminth Proteins
- Male
- Models, Genetic
- Molecular Sequence Data
- Motor Neurons
- Movement
- Mutation
- Nerve Tissue Proteins