Article
C. elegans unc-4 gene encodes a homeodomain protein that determines the pattern of synaptic input to specific motor neurons.
Nature - 27 Feb 1992
Miller D M, Shen M M, Shamu C E, Bürglin T R, Ruvkun G, Dubois M L, Ghee M, Wilson L
Abstract excerpt
The creation of neural circuits depends on the formation of synapses between specific sets of neurons. Little is known, however, of the molecular mechanisms governing synaptic choice. A mutation in the unc-4 gene alters the pattern of synaptic input to one class of motor neurons in the Caenorhabd...
Topics
- Alleles
- Amino Acid Sequence
- Animals
- Base Sequence
- Blotting, Southern
- Caenorhabditis
- Caenorhabditis elegans Proteins
- Cosmids
- DNA
- Genes, Homeobox
- Genome
- Helminth Proteins
- Homeodomain Proteins
- Molecular Sequence Data
- Motor Neurons