Article
Mutations in the Caenorhabditis elegans unc-4 gene alter the synaptic input to ventral cord motor neurons.
Nature - 27 Feb 1992
White J G, Southgate E, Thomson J N
Abstract excerpt
Identification of the genes orchestrating neurogenesis would greatly enhance our understanding of this process. Genes have been identified that specify neuron type (for example cut and numb in Drosophila and mec-3 in Caenorhabditis elegans) and process guidance (for example, unc-5, unc-6 and unc-40 in C. elegans and the fas-1 gene of Drosophila). We sought genes defining synaptic specificity by identifying...
Topics
- Animals
- Caenorhabditis
- Genes
- Intercellular Junctions
- Microscopy, Electron
- Models, Neurological
- Motor Neurons
- Mutation
- Synapses