Mechanism of K562-induced human natural killer cell inactivation using highly enriched effector cells isolated via a new single-step sheep erythrocyte rosette assay.

doi:10.1016/0769-2625(88)90064-5

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Article

Mechanism of K562-induced human natural killer cell inactivation using highly enriched effector cells isolated via a new single-step sheep erythrocyte rosette assay.

Annales de l'Institut Pasteur. Immunology - 1 Jan 2000

Abrams S I, Brahmi Z

Abstract excerpt

In this study, we used preparations highly enriched in human natural killer (NK) cells to further characterize the mechanism of target-cell-induced NK inactivation. Highly enriched populations of NK cells were obtained by a newly developed, single-step sheep red blood cell rosette assay. This met...

Topics

Animals
Antibody-Dependent Cell Cytotoxicity
Cell Separation
Humans
Killer Cells, Natural
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Phenotype
Rosette Formation
Sheep

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