Allele frequencies of DNA markers genetically linked to Friedreich ataxia in the German population.

doi:10.1159/000154121

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Article

Allele frequencies of DNA markers genetically linked to Friedreich ataxia in the German population.

Human heredity - 1 Jan 2000

Zühlke C, Thies U

Abstract excerpt

Friedreich ataxia (FRDA) is a recessive neurodegenerative disorder affecting both central and peripheral nervous systems. The mutation was mapped to chromosome 9 by its tight linkage to the polymorphic loci D9S5 and D9S15. Using informative DNA markers the allele frequencies at these loci, in up...

Topics

Alleles
Blotting, Southern
Chromosomes, Human, Pair 9
DNA
DNA Probes
Friedreich Ataxia
Gene Frequency
Genetic Linkage
Genetic Markers
Germany
Humans
Polymorphism, Restriction Fragment Length

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