Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Allele frequencies of DNA markers genetically linked to Friedreich ataxia in the German population.

Human heredity - 1 Jan 2000

Zühlke C, Thies U

Abstract excerpt

Friedreich ataxia (FRDA) is a recessive neurodegenerative disorder affecting both central and peripheral nervous systems. The mutation was mapped to chromosome 9 by its tight linkage to the polymorphic loci D9S5 and D9S15. Using informative DNA markers the allele frequencies at these loci, in up to 84 unrelated healthy persons and in 16 FRDA patients of German origin, were determined. The comparison to data from...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alleles
Share to Blotting, Southern
Share to DNA

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to DNA Probes

Share to Gene Frequency

Share to Genetic Linkage

Share to Genetic Markers

Share to Polymorphism, Restriction Fragment Length

Source

Identifiers

PMID: 8103037
DOI: 10.1159/000154121

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 9 closest

Allele frequencies of DNA markers genetically linked to Friedreich ataxia in the German population.PMID 8103037Read ↗

Linkage disequilibrium analysis of Friedreich's ataxia in 140 Caucasian families: positioning of the disease locus and evaluation of allelic heterogeneity.Semantic proximity Read ↗

Friedreich's disease. A linkage study in southern and central Italy.Semantic proximity Read ↗

The Friedreich ataxia gene is assigned to chromosome 9q13-q21 by mapping of tightly linked markers and shows linkage disequilibrium with D9S15.Semantic proximity Read ↗

Friedreich ataxia in Italian families: genetic homogeneity and linkage disequilibrium with the marker loci D9S5 and D9S15.Semantic proximity Read ↗

Identification of a hypervariable microsatellite polymorphism within D9S15 tightly linked to Friedrich's ataxia.Semantic proximity Read ↗

Evidence of a genetic marker associated with early onset in Friedreich's ataxia.Semantic proximity Read ↗

Allele frequencies and linkage disequilibrium of polymorphic DNA markers of the Huntington disease region in the German population.Semantic proximity Read ↗

Localization of the gene for familial dysautonomia on chromosome 9 and definition of DNA markers for genetic diagnosis.Semantic proximity Read ↗

Locus heterogeneity in Friedreich ataxia.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.