Complement C4 and heat shock protein 70 (HSP70) genotypes and type I diabetes mellitus.

doi:10.1007/BF00241637

Back to search

Article

Complement C4 and heat shock protein 70 (HSP70) genotypes and type I diabetes mellitus.

Immunogenetics - 1 Jan 1990

Caplen N J, Patel A, Millward A, Campbell R D, Ratanachaiyavong S, Wong F S, Demaine A G

Abstract excerpt

Type I diabetes is strongly associated with the major histocompatibility complex (MHC) class II region (DR and DQ loci), and to a lesser extent the class III region (complement C4 loci). Restriction fragment length polymorphism analysis was employed to investigate the C4 and heat shock protein 70...

Topics

Complement C4
Diabetes Mellitus, Type 1
Gene Frequency
Genotype
HLA Antigens
HLA-DR Antigens
Heat-Shock Proteins
Humans

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.