Article
Complement C4 and heat shock protein 70 (HSP70) genotypes and type I diabetes mellitus.
Immunogenetics - 1 Jan 1990
Caplen N J, Patel A, Millward A, Campbell R D, Ratanachaiyavong S, Wong F S, Demaine A G
Abstract excerpt
Type I diabetes is strongly associated with the major histocompatibility complex (MHC) class II region (DR and DQ loci), and to a lesser extent the class III region (complement C4 loci). Restriction fragment length polymorphism analysis was employed to investigate the C4 and heat shock protein 70 (HSP70) loci of 176 patients with type I diabetes and 92 healthy controls. In the patient population there was an...
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