Postnatal ocular expression of tyrosinase and related proteins: disruption by the pink-eyed unstable (p(un)) mutation.

doi:10.1006/exer.1993.1128

Back to search

Article

Postnatal ocular expression of tyrosinase and related proteins: disruption by the pink-eyed unstable (p(un)) mutation.

Experimental eye research - 1 Sept 1993

Chiu E, Lamoreux M L, Orlow S J

Abstract excerpt

Ocular pigmentation in the mouse occurs primarily postnatally as a result of the melanization of neural crest-derived melanocytes. Using immunologic and biochemical techniques, we demonstrate that in normal mice the expression of tyrosinase and the related proteins TRP-1 and TRP-2, rises during t...

Topics

Albinism
Animals
Electrophoresis, Polyacrylamide Gel
Eye
Eye Color
Mice
Mice, Inbred C57BL
Molecular Weight
Monophenol Monooxygenase
Mutation
Time Factors
Tyrosine 3-Monooxygenase

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.