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Article

A mouse TRAPP-related protein is involved in pigmentation.

Genomics - 1 Aug 2006

Gwynn Babette, Smith Richard S, Rowe Lucy B, Taylor Benjamin A, Peters Luanne L

Abstract excerpt

We identified a new spontaneous recessive mutation in the mouse, mhyp (mosaic hypopigmentation), in a screen for novel proviral integration sites in a multiple ecotropic provirus mapping stock. Integration of an 8.4-kb retrovirus results in mosaic loss of coat pigment in mhyp homozygotes. Patchy loss of pigmentation in the retinal pigmented epithelial layer of the eye with abnormal melanosomes is also evident. We...

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PMID: 16697553
DOI: 10.1016/j.ygeno.2006.04.002

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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