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Are Hippocampal Hypoperfusion and ATP Depletion Prime Movers in the Genesis of Alzheimer’s Disease? A Review of Recent Pertinent Observations from Molecular Biology

2025-06-25

Abstract excerpt

Alzheimers dementia (AD) is a disease of aging brain. It begins in the hippocampal region with the epicentre in the entorhinal cortex, then gradually extends into adjacent brain areas involved in memory and cognition. The events which initiate the damage are unknown and under intense investigation. Localisation to the hippocampus can now be explained by anatomical features of the blood vessels supplying this regio...

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Literature Corpus work: d6b9f8a0-1cfa-56bb-bebd-923f83a57ece
DOI: 10.20944/preprints202506.1793.v2

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