Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

nov: a new genetic locus that affects the response of Escherichia coli K-12 to novobiocin.

Molecular microbiology - 1 Jun 1992

Rakonjac J, Milic M, Ajdic-Predic D, Santos D, Ivanisevic R, Savic D J

Abstract excerpt

We have identified a new gene locus (nov) affecting the resistance of Escherichia coli K-12 to novobiocin. The gene also affects, although to a lesser extent, tolerance to another gyrase inhibitor coumermycin. Transductional and complementation analysis show that nov is located between att phi 80 and the osmZ (hns) genes at minute 27 of the E. coli K-12 genetic map. In standard laboratory strains of E. coli K-12...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alleles
Share to Biological Transport
Share to Chromosome Mapping

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to DNA, Bacterial

Share to Drug Resistance, Microbial

Share to Escherichia coli

Share to Genes, Bacterial

Share to Mutation

Source

Identifiers

PMID: 1625583
DOI: 10.1111/j.1365-2958.1992.tb00876.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

nov: a new genetic locus that affects the response of Escherichia coli K-12 to novobiocin.PMID 1625583Read ↗

Nucleotide sequence, mutational analysis, transcriptional start site, and product analysis of nov, the gene which affects Escherichia coli K-12 resistance to the gyrase inhibitor novobiocin.Semantic proximity Read ↗

Identity of the Escherichia coli cls and nov genes.Semantic proximity Read ↗

NovJ/NovK catalyze benzylic oxidation of a beta-hydroxyl tyrosyl-S-pantetheinyl enzyme during aminocoumarin ring formation in novobiocin biosynthesis.Semantic proximity Read ↗

Identification of two new genetically active regions associated with the osmZ locus of Escherichia coli: role in regulation of proU expression and mutagenic effect of cya, the structural gene for adenylate cyclase.Semantic proximity Read ↗

Cloning and sequencing of the hemE gene encoding uroporphyrinogen III decarboxylase (UPD) from Escherichia coli K-12.Semantic proximity Read ↗

Analysis of the endA mutation of Escherichia coli K12 strains: JM103 behaves like endA+ wild-type strains.Semantic proximity Read ↗

cysB and cysE mutants of Escherichia coli K12 show increased resistance to novobiocin.Semantic proximity Read ↗

Menaquinone (vitamin K2) biosynthesis: localization and characterization of the menE gene from Escherichia coli.Semantic proximity Read ↗

soxR, a locus governing a superoxide response regulon in Escherichia coli K-12.Semantic proximity Read ↗

Plasmids bearing hfq and the hns-like gene stpA complement hns mutants in modulating arginine decarboxylase gene expression in Escherichia coli.Semantic proximity Read ↗

Alteration of Escherichia coli topoisomerase IV to novobiocin resistance.Semantic proximity Read ↗

Clorobiocin biosynthesis in Streptomyces: identification of the halogenase and generation of structural analogs.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.