Article
nov: a new genetic locus that affects the response of Escherichia coli K-12 to novobiocin.
Molecular microbiology - 1 Jun 1992
Rakonjac J, Milic M, Ajdic-Predic D, Santos D, Ivanisevic R, Savic D J
Abstract excerpt
We have identified a new gene locus (nov) affecting the resistance of Escherichia coli K-12 to novobiocin. The gene also affects, although to a lesser extent, tolerance to another gyrase inhibitor coumermycin. Transductional and complementation analysis show that nov is located between att phi 80...
Topics
- Alleles
- Aminocoumarins
- Biological Transport
- Cell Membrane Permeability
- Chromosome Mapping
- Coumarins
- DNA, Bacterial
- DNA, Superhelical
- Drug Resistance, Microbial
- Escherichia coli
- Genes, Bacterial
- Genes, Suppressor
- Mutation
- Novobiocin