Identity of the Escherichia coli cls and nov genes.

doi:10.1128/jb.177.17.5155-5157.1995

Back to search

Article

Identity of the Escherichia coli cls and nov genes.

Journal of bacteriology - 1 Sept 1995

Tropp B E, Ragolia L, Xia W, Dowhan W, Milkman R, Rudd K E, Ivanisević R, Savić D J

Abstract excerpt

cls and nov mutants have similar increased sensitivities to novobiocin and reduced levels of cardiolipin, both of which can be corrected by plasmid-borne copies of either wild-type gene. A comparison of the DNA sequences of both genes further verifies their identity.

Topics

Escherichia coli
Genes, Bacterial
Genetic Complementation Test
Genotype
Membrane Proteins
Mutation
Novobiocin
Phosphatidylethanolamines
Phosphatidylglycerols
Transferases (Other Substituted Phosphate Groups)

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.