Article
Liver cirrhosis associated with heterozygous alpha-1-antitrypsin deficiency type Pi MS and autoimmune features.
Digestion - 1 Jan 1995
Löhr H F, Schlaak J F, Dienes H P, Lorenz J, Meyer zum Büschenfelde K H, Gerken G
Abstract excerpt
Patients with homozygous protease inhibitor (Pi) type ZZ or a few rare M-like types may develop liver cirrhosis due to intracellular storage of alpha-antitrypsin (AAT), whereas some patients with heterozygous Pi MZ or SZ normally present with transient abnormal liver function tests in childhood. We report a 42-year-old obese patient who developed liver cirrhosis in association with heterozygous Pi MS (AAT)...
Topics
- Adult
- Alcoholism
- Autoimmune Diseases
- Cytokines
- Flow Cytometry
- Heterozygote
- Humans
- Immunoenzyme Techniques
- Liver
- Liver Cirrhosis
- Male
- Microscopy, Electron