Article
Alpha-1-antitrypsin phenotypes in adult liver disease patients.
Upsala journal of medical sciences - 1 Jan 2009
Topic Aleksandra, Alempijevic Tamara, Milutinovic Aleksandra Sokic, Kovacevic Nada
Abstract excerpt
Alpha-1-antitrypsin (AAT) is an important serine protease inhibitor in humans. Hereditary alpha-1-antitrypsin deficiency (AATD) affects lungs and liver. Liver disease caused by AATD in paediatric patients has been previously well documented. However, the association of liver disease with alpha-1-antitrypsin gene polymorphisms in adults is less clear. Therefore, we aimed to study AAT polymorphisms in adults with...
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