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Targeting MDM2-p53 interaction for breast cancer therapy

31 Dec 2024

Abstract excerpt

upregulation in cells with wild-type or mutated TP53. MDM2 inhibitors (MDM2i) are administered in combination with existing chemotherapies to reduce their effects on healthy cells. Few clinical and preclinical studies have been conducted using MDM2i, which necessitates high-quality clinical trials to support their therapeutic potential in breast cancer therapy.

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 40191734
DOI: 10.32604/or.2025.058956

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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