Article
Analysis of retroorbital T cell antigen receptor variable region gene usage in patients with Graves' ophthalmopathy.
European journal of endocrinology - 1 Mar 1995
Heufelder A E, Herterich S, Ernst G, Bahn R S, Scriba P C
Abstract excerpt
To date, it has remained unclear whether orbit-infiltrating T cells in patients with Graves' ophthalmopathy (GO) represent a primary immune response in which a limited number of T cell clones driving the disease are activated against specific antigens, or whether they participate in a non-specific inflammatory process. To characterize these T cells at the molecular level, we examined the T cell antigen receptor...
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