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Article

Genetic diversity of the highly variable V1 region interferes with Human Immunodeficiency Virus type 1 envelope functionality.

Retrovirology - 24 Oct 2013

Hamoudi Meriem, Simon-Loriere Etienne, Gasser Romain, Negroni Matteo

Abstract excerpt

BACKGROUND: The HIV envelope (Env) promotes viral entry in the host cell. During this process, Env undergoes several conformational changes to ensure its function. At the same time, the gp120 component of Env is the protein of the virus presenting the largest genetic diversity. Understanding how the virus maintains the balance between the competing requirements for maintenance of functionality and antigenic...

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Identifiers

PMID: 24156625
DOI: 10.1186/1742-4690-10-114
PMCID: PMC3826872

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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