Article
Genetic diversity of human immunodeficiency virus type 2: evidence for distinct sequence subtypes with differences in virus biology.
Journal of virology - 1 Nov 1994
Gao F, Yue L, Robertson D L, Hill S C, Hui H, Biggar R J, Neequaye A E, Whelan T M, Ho D D, Shaw G M
Abstract excerpt
The virulence properties of human immunodeficiency virus type 2 (HIV-2) are known to vary significantly and to range from relative attenuation in certain individuals to high-level pathogenicity in others. These differences in clinical manifestations may, at least in part, be determined by genetic differences among infecting virus strains. Evaluation of the full spectrum of HIV-2 genetic diversity is thus a...
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