The predominant virus antigen burden is present in macrophages in Theiler's murine encephalomyelitis virus-induced demyelinating disease.

doi:10.1128/JVI.69.4.2525-2533.1995

Back to search

Article

The predominant virus antigen burden is present in macrophages in Theiler's murine encephalomyelitis virus-induced demyelinating disease.

Journal of virology - 1 Apr 1995

Lipton H L, Twaddle G, Jelachich M L

Abstract excerpt

Theiler's murine encephalomyelitis virus (TMEV) produces a persistent central nervous system infection and chronic, inflammatory demyelinating disease in susceptible mice. TMEV antigen(s) and RNA genome have been detected in astrocytes, oligodendrocytes, and macrophages during persistence. Whethe...

Topics

Animals
Antibodies, Monoclonal
Antigens, Viral
Astrocytes
Demyelinating Diseases
Fluorescent Antibody Technique
Macrophages
Mice
Phenotype
Poliomyelitis
Theilovirus

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.