Article
Role of macrophages during Theiler's virus infection.
Journal of virology - 1 Apr 1997
Rossi C P, Delcroix M, Huitinga I, McAllister A, van Rooijen N, Claassen E, Brahic M
Abstract excerpt
Theiler's virus, a murine picornavirus, causes a persistent infection of the central nervous system with chronic inflammation and primary demyelination. We examined the nature of infected cells at different times postinoculation (p.i.) with a combined immunocytochemistry-in situ hybridization assay. The virus was found in the gray matter of the brain, mostly in neurons, during the first week p.i. During the...
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