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Article

Expression of the mannose receptor CD206 in HIV and SIV encephalitis: a phenotypic switch of brain perivascular macrophages with virus infection.

Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology - 1 Dec 2014

Holder Gerard E, McGary Christopher M, Johnson Edward M, Zheng Rubo, John Vijay T, Sugimoto Chie, Kuroda Marcelo J, Kim Woong-Ki

Abstract excerpt

We examined the expression of the mannose receptor CD206 by perivascular macrophages (PVM) in normal human and monkey brains and in brains of HIV-infected humans and of monkeys infected with simian immunodeficiency virus (SIV). Depletion of brain PVM in SIV-infected monkeys by intrathecal injection of liposome-encapsulated bisphosphonates eliminated CD206-expressing cells in the brain, confirming their...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 25146376
DOI: 10.1007/s11481-014-9564-y
PMCID: PMC4364002

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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