[Debrisoquine hydroxylation test as an example of new possibilities of research in psychopharmacology].

Article

[Debrisoquine hydroxylation test as an example of new possibilities of research in psychopharmacology].

Psychiatria polska - 1 Jan 2000

Jarema M

Abstract excerpt

About 5-10% of European white population has a genetically determinant defect of the CYP2D6, one of the enzymes of cytochrome P-450. This defect leads to the impaired metabolism of many drugs including various psychopharmacological agents. The measurement of the hydroxylation of debrisoquine is a...

Topics

Biotransformation
Cytochrome P-450 Enzyme System
Debrisoquin
Humans
Hydroxylation
Phenotype
Psychopharmacology

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