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Article

[The importance of examining genetic polymorphism of drug oxidation in psychiatry].

Psychiatria polska - 1 Jan 2000

Beszłej J A, Kiejna A

Abstract excerpt

The paper describes: 1. Drug oxidation process. 2. Cytochrome P-450 Isozymes. 3. Genetic polimorphism of drug oxidation. 4. Spartein test. Metabolic ratio, extensive and poor metabolizers. 5. Cytochrom P-450 and drug metabolism. 6. Inhibition of drug oxidation process and inhibitors of CYP450. 7. Influence of CYP450 genetic polimorphism on development of diseases. 8. Clinical value of examining the genetic...

Topics

Biotransformation
Cytochrome P-450 Enzyme System
Humans
Isoenzymes
Liver
Mephenytoin
Metabolic Diseases
Oxidation-Reduction
Phenotype
Polymorphism, Genetic
Psychiatry
Sparteine

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Identifiers

PMID: 7878153

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7878153-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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