Article
[Cytochrome p450 IID6, its role in psychopharmacology].
Annales medico-psychologiques - 1 Feb 1995
Lamard L, Pérault M C, Bouquet S, Guibert S
Abstract excerpt
Cytochrome P450 IID6 has got typical features (genetical polymorphism, competitive inhibition, saturability) which can be at the origin of pharmacokinetic modifications of molecules using it for their metabolism. In the field of pharmacology, many molecules are substrates or inhibitors of this cy...
Topics
- Adolescent
- Adult
- Aged
- Clomipramine
- Cytochrome P-450 CYP2D6
- Cytochrome P-450 Enzyme System
- Depressive Disorder
- Dextromethorphan
- Humans
- Middle Aged
- Mixed Function Oxygenases
- Phenotype
- Psychiatric Status Rating Scales