Regulation of MAPKs by growth factors and receptor tyrosine kinases.

doi:10.1016/j.bbamcr.2007.01.002

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Back to search

Article

Regulation of MAPKs by growth factors and receptor tyrosine kinases.

Biochimica et biophysica acta - 1 Aug 2007

Katz Menachem, Amit Ido, Yarden Yosef

Abstract excerpt

Multiple growth- and differentiation-inducing polypeptide factors bind to and activate transmembrane receptors tyrosine kinases (RTKs), to instigate a plethora of biochemical cascades culminating in regulation of cell fate. We concentrate on the four linear mitogen-activated protein kinase (MAPK) cascades, and highlight organizational and functional features relevant to their action downstream to RTKs. Two...

Topics

Animals
Cell Movement
Cell Proliferation
Endocytosis
Feedback
Gene Expression Regulation
Growth Substances
Humans
MAP Kinase Signaling System
Models, Biological
Mutation
Neoplasms
Oncogenes
Phosphorylation
RNA-Binding Proteins
Receptor Cross-Talk
Receptor Protein-Tyrosine Kinases

Source

Open in PubMed Open full text

Identifiers

PMID: 17306385
DOI: 10.1016/j.bbamcr.2007.01.002
PMCID: PMC2758354

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics