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Article

Regulation of MAPKs by growth factors and receptor tyrosine kinases.

Biochimica et biophysica acta - 1 Aug 2007

Katz Menachem, Amit Ido, Yarden Yosef

Abstract excerpt

Multiple growth- and differentiation-inducing polypeptide factors bind to and activate transmembrane receptors tyrosine kinases (RTKs), to instigate a plethora of biochemical cascades culminating in regulation of cell fate. We concentrate on the four linear mitogen-activated protein kinase (MAPK) cascades, and highlight organizational and functional features relevant to their action downstream to RTKs. Two...

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Identifiers

PMID: 17306385
DOI: 10.1016/j.bbamcr.2007.01.002
PMCID: PMC2758354

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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