Article
Stable secretion of a soluble, oligomeric form of rabies virus glycoprotein: influence of N-glycan processing on secretion.
Biochemistry - 28 Feb 1995
Wojczyk B, Shakin-Eshleman S H, Doms R W, Xiang Z Q, Ertl H C, Wunner W H, Spitalnik S L
Abstract excerpt
Rabies virus glycoprotein (RGP) is a 505 amino acid type I transmembrane glycoprotein that is important in the pathogenesis of rabies virus infection. RGP also stimulates the development of neutralizing antibodies by the host. N-linked glycosylation is required for both cell surface expression an...
Topics
- Animals
- Antigens, Viral
- CHO Cells
- Carbohydrate Sequence
- Cricetinae
- Glycoproteins
- Glycosylation
- Immunochemistry
- Molecular Sequence Data
- Mutation
- Polysaccharides
- Protein Conformation
- Protein Processing, Post-Translational
- Rabies virus
- Solubility
- Transfection
- Viral Envelope Proteins