Article
N-linked glycan in tick-borne encephalitis virus envelope protein affects viral secretion in mammalian cells, but not in tick cells.
The Journal of general virology - 1 Oct 2013
Yoshii Kentaro, Yanagihara Natsumi, Ishizuka Mariko, Sakai Mizuki, Kariwa Hiroaki
Abstract excerpt
Tick-borne encephalitis virus (TBEV) is a zoonotic disease agent that causes severe encephalitis in humans. The envelope protein E of TBEV has one N-linked glycosylation consensus sequence, but little is known about the biological function of the N-linked glycan. In this study, the function of protein E glycosylation was investigated using recombinant TBEV with or without the protein E N-linked glycan. Virion...
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