Article
Effects of truncation of the carboxy terminus of pseudorabies virus glycoprotein B on infectivity.
Journal of virology - 1 Aug 2000
Nixdorf R, Klupp B G, Karger A, Mettenleiter T C
Abstract excerpt
Glycoproteins homologous to the type I membrane glycoprotein B (gB) of herpes simplex virus 1 (HSV-1) are the most highly conserved glycoproteins within the family Herpesviridae and are present in members of each herpesvirus subfamily. In the alphaherpesvirus pseudorabies virus (PrV), gB is required for entry into target cells and for direct viral cell-to-cell spread. These processes, though related, appear to be...
Topics
- Amino Acid Sequence
- Animals
- Cell Line
- Genetic Complementation Test
- Herpesvirus 1, Suid
- Microscopy, Confocal
- Molecular Sequence Data
- Mutation
- Protein Structure, Tertiary
- Rabbits
- Recombination, Genetic
- Viral Envelope Proteins
- Viral Plaque Assay
- Virion
