Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Conformationally appropriate expression of the Toxoplasma antigen SAG1 (p30) in CHO cells

1 Jan 1994

Abstract excerpt

The Toxoplasma gondii major surface antigen, called SAG1 or p30, is a highly immunogenic protein which has generated great interest as a diagnostic reagent, as a potential subunit vaccine, and for its role in invasion. Unfortunately, bacterial recombinant protein is grossly misfolded so that, for example, it is not effectively recognized by antibodies to native SAG1. To overcome this, we have turned to expression...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bacteriophages and microbial interactions
Share to Herpesvirus Infections and Treatments
Share to Toxoplasma gondii Research Studies

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 8262628
DOI: 10.1128/iai.62.1.203-209.1994

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Conformationally appropriate expression of the Toxoplasma antigen SAG1 (p30) in CHO cellsPMID 8262628Read ↗

Design and evaluation of a recombinant multi-epitope antigen for serodiagnosis of Toxoplasma gondii infection in humansSemantic proximity Read ↗

Toxoplasma gondii: stable complementation of sag1 (p30) mutants using SAG1 transfection and fluorescence-activated cell sorting.Semantic proximity Read ↗

Direct enzyme-linked aptamer assay (DELAA) for diagnosis of toxoplasmosis by detection of SAG1 protein in mice and humansSemantic proximity Read ↗

Surface antigens of Toxoplasma gondii: variations on a theme.Semantic proximity Read ↗

Analysis of the SAG5 locus reveals a distinct genomic organisation in virulent and avirulent strains of Toxoplasma gondii.Semantic proximity Read ↗

High-level expression of the monomeric SARS-CoV-2 S protein RBD 320-537 in stably transfected CHO cells by the <i>EEF1A1</i> -based plasmid vectorSemantic proximity Read ↗

The fusion of <i>Toxoplasma gondii</i> SAG1 vaccine candidate to <i>Leishmania infantum</i> heat shock protein 83‐kDa improves expression levels in tobacco chloroplastsSemantic proximity Read ↗

Induction of partial protection against infection with Toxoplasma gondii genotype II by DNA vaccination with recombinant chimeric tachyzoite antigens.Semantic proximity Read ↗

Development of a stable Leishmania expression vector and application to the study of parasite surface antigen genes.Semantic proximity Read ↗

The Toxoplasma surface protein SAG1 triggers efficient in vitro secretion of chemokine ligand 2 (CCL2) from human fibroblasts.Semantic proximity Read ↗

Effect of Codon Optimization on Expression Levels of a Functionally Folded Malaria Vaccine Candidate in Prokaryotic and Eukaryotic Expression SystemsSemantic proximity Read ↗

A Search for Trypanosoma brucei rhodesiense Diagnostic Antigens by Proteomic Screening and Targeted CloningSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.