Article
Malignant transformation of the human endometrium is associated with overexpression of lactoferrin messenger RNA and protein.
Cancer research - 1 Mar 1995
Walmer D K, Padin C J, Wrona M A, Healy B E, Bentley R C, Tsao M S, Kohler M F, McLachlan J A, Gray K D
Abstract excerpt
In the mouse uterus, lactoferrin is a major estrogen-inducible uterine secretory protein, and its expression correlates directly with the period of peak epithelial cell proliferation. In this study, we examine the expression of lactoferrin mRNA and protein in human endometrium, endometrial hyperplasias, and adenocarcinomas using immunohistochemistry, Western immunoblotting, and Northern and in situ RNA...
Topics
- Adenocarcinoma
- Adult
- Aged
- Blotting, Northern
- Cell Transformation, Neoplastic
- Endometrial Hyperplasia
- Endometrial Neoplasms
- Endometrium
- Female
- Humans
- Immunohistochemistry