Article
Neoplastic transformation of the endocervix associated with downregulation of lactoferrin expression.
Molecular carcinogenesis - 1 Oct 1997
Farley J, Loup D, Nelson M, Mitchell A, Esplund G, Macri C, Harrison C, Gray K
Abstract excerpt
The incidence of cervical adenocarcinomas in young women over the last two decades has increased. Even with increasing knowledge of the role of human papillomavirus in the etiology of adenocarcinoma of the cervix, there is a paucity of data concerning the genetic and epigenetic factors that contr...
Topics
- Adenocarcinoma
- Cell Death
- Cell Division
- Cell Transformation, Neoplastic
- Cervix Uteri
- Down-Regulation
- Female
- Humans
- Immunohistochemistry
- In Situ Hybridization
- Lactoferrin
- Neoplasm Invasiveness
- Phenotype
- RNA, Messenger
- RNA, Neoplasm
- Receptors, Estrogen
- Receptors, Progesterone
- Tumor Suppressor Protein p53