Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic association between dopamine transporter protein alleles and cocaine-induced paranoia.

Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology - 1 Nov 1994

Gelernter J, Kranzler H R, Satel S L, Rao P A

Abstract excerpt

Paranoia in the context of cocaine abuse is common and potentially dangerous. Several lines of evidence suggest that this phenomenon may be related to function of the dopamine transporter protein (DAT). DAT is the site of presynaptic reuptake of dopamine, an event that terminates its synaptic activity. The gene coding for dopamine transporter protein (DAT1) contains a variable number of tandem repeats (VNTR)...

Topics

Adult
Alleles
Carrier Proteins
Cocaine
Dopamine Plasma Membrane Transport Proteins
Female
Genotype
Humans
Male
Membrane Glycoproteins
Membrane Transport Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Nerve Tissue Proteins

Paranoid Disorders

Polymerase Chain Reaction

Polymorphism, Genetic

Substance-Related Disorders

Source

Identifiers

PMID: 7865100
DOI: 10.1038/sj.npp.1380106

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7865100-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic association between dopamine transporter protein alleles and cocaine-induced paranoia.PMID 7865100Read ↗

Association between polymorphisms in catechol-O-methyltransferase (COMT) and cocaine-induced paranoia in European-American and African-American populations.Semantic proximity Read ↗

Dopamine beta-hydroxylase gene (DbetaH) -1021C-->T influences self-reported paranoia during cocaine self-administration.Semantic proximity Read ↗

Risk factors for cocaine-induced paranoia in cocaine-dependent sibling pairs.Semantic proximity Read ↗

Could the inter-individual variability in cocaine-induced psychotic effects influence the development of cocaine addiction? Towards a new pharmacogenetic approach to addictions.Semantic proximity Read ↗

A dopamine transporter gene functional variant associated with cocaine abuse in a Brazilian sample.Semantic proximity Read ↗

Association of variants in MANEA with cocaine-related behaviors.Semantic proximity Read ↗

No association between polymorphisms in the serotonin transporter gene and susceptibility to cocaine dependence among African-American individuals.Semantic proximity Read ↗

Human clock, PER1 and PER2 polymorphisms: lack of association with cocaine dependence susceptibility and cocaine-induced paranoia.Semantic proximity Read ↗

Adolescent cannabis use increases risk for cocaine-induced paranoia.Semantic proximity Read ↗

Genomewide linkage scan for cocaine dependence and related traits: significant linkages for a cocaine-related trait and cocaine-induced paranoia.Semantic proximity Read ↗

Genetic variation of the dopamine transporter (DAT1) influences the acute subjective responses to cocaine in volunteers with cocaine use disorders.Semantic proximity Read ↗

Human dopamine transporter gene polymorphism (VNTR) and alcoholism.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.