N-nitrosomethylurea-induced carcinogenesis in the progeny of male rats of different ages.

doi:10.1016/0921-8734(95)90007-1

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Article

N-nitrosomethylurea-induced carcinogenesis in the progeny of male rats of different ages.

Mutation research - 1 Feb 1995

Anisimov V N, Gvardina O E

Abstract excerpt

Three-month-old male and 3-month-old female LIO rats as well as 25-month-old males and 3-month-old females were mated and at the age of 3 months their progeny were exposed to a single intravenous injection of N-nitrosomethylurea (MNU) at the dose of 20 mg/kg of body weight or solvent. Animals wer...

Topics

Animals
Female
Genetic Predisposition to Disease
Genomic Imprinting
Germ-Line Mutation
Kidney Neoplasms
Male
Methylnitrosourea
Paternal Age
Rats

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